Current trends in <i>Helicobacter pylori</i> eradication therapy

نویسندگان

چکیده

According to the Maastricht VI consensus, triple therapy (PPI + clarithromycin amoxicillin) and bismuth-based quadruple bismuth tetracycline metronidazole) are considered may be proscribed empirically as first-line regimens in regions with low resistance rates (<15%). In high (> 15%), well unknown this antibacterial agent, it is recommended use classical drugs main choice without (“simultaneous” or “concomitant”) an alternative. The second-line of empiric (when antimicrobial susceptibility testing not available) include fluoroquinolone-based levofloxacin amoxicillin bismuth) therapy. consensus regulates rifabutin-based rifabutin) a “rescue” therapy, if above ET schemes ineffective there no possibility conduct test. its latest clinical guidelines, Russian Gastroenterological Association (RGA) recommends view achieving maximum treatment efficiency during classic levelling risk further progression Russia take additional measures increase effectiveness (detailed instruction patient control over strict adherence prescribed regimen, prolonging course up 14 days; prescribing PPI at increased dose twice day; generation PPIs (rabeprazole esomeprazole); adding tripotassium dicitrate (240 mg 2 times day) standard therapy; cytoprotector rebamipide (100 3 probiotic proven efficacy within controlled studies).

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ژورنال

عنوان ژورنال: ??????????? ?????

سال: 2023

ISSN: ['0235-1188', '2618-8961']

DOI: https://doi.org/10.21518/ms2023-134